The emergence of new types of SARS-CoV-2 virus has caused great concern around the world. Subsequent mutations reveal new and increasingly dangerous diseases for the body. The Indian mutation of the virus, that is, the delta variant, is particularly dangerous. However, the latest discovery of scientists gives hope to a certain group of people who have received exceptional protection against the delta variant. Who cares about the latest research?
One of the early mutations in the spike protein (D614G) that alters the balance between the open and closed configuration of the protein without modifying the antibody equivalence, has become prevalent in the world. Since then, different types of the virus of interest have spread globally. New variants of the SARS-CoV-2 virus with mutations in key elements of identification mean that scientists are constantly studying the effects of the COVID-19 vaccine. Recent analyzes looked at vaccine efficacy for the delta variant. Scientists investigated which group of people is best protected from deltas.
Delta variant: Best protection for vaccinated healers
French researchers analyzed the immune response elicited by mRNA vaccination in infected and previously uninfected patients. Studies have shown that people vaccinated with an mRNA vaccine against COVID-19 who contracted the disease neutralized the delta variant of SARS-CoV-2 compared to previously uninfected people.
Scientists: Memory cells can last for decades. They provide immune protection
In addition to the immunoglobulins present in serum, another “layer” of immune protection is the generation of memory B cells against SARS-CoV-2. The so-called memory cells, or memory lymphocytes, are B lymphocytes formed during the first (initial) infection of the pathogen. After infection, memory cells remain in the body, ready to be transformed into plasma cells, which can produce large amounts of antibodies in a short time if the same type of pathogenic microorganism appears in the body.
Memory cells can survive for decades, allowing them to respond to multiple exposures to the same antigen. New research finds that vaccination increases MBC activity in patients who have recovered from COVID-19. MBCs maintain their diversity and produce potent antibodies that neutralize the various variants of the SARS-CoV-2 coronavirus.
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